Anpirtoline is a potent agonist of the 5-HT1B receptor, exhibiting a Ki of 28 nM for this target, alongside 150 nM for 5-HT1A and 1.49 μM for 5-HT2 receptors. This compound demonstrates notable serotonergic activity and has been linked to antinociceptive and antidepressant-like effects. Anpirtoline is primarily utilized in research to explore its potential therapeutic applications in mood disorders and pain management.
Anpirtoline is a potent agonist of the 5-HT1B receptor, exhibiting a Ki of 28 nM for this target, alongside 150 nM for 5-HT1A and 1.49 μM for 5-HT2 receptors. This compound demonstrates notable serotonergic activity and has been linked to antinociceptive and antidepressant-like effects. Anpirtoline is primarily utilized in research to explore its potential therapeutic applications in mood disorders and pain management.
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