Antalarmin is a selective, nonpeptide antagonist of corticotropin-releasing factor receptor 1 (CRHR1), with a Ki of 2.7 nM. It is capable of crossing the blood–brain barrier, making it a valuable compound for investigating CRHR1-mediated central nervous system functions and stress-related disorders.
Antalarmin is a selective, nonpeptide antagonist of corticotropin-releasing factor receptor 1 (CRHR1), with a Ki of 2.7 nM. It is capable of crossing the blood–brain barrier, making it a valuable compound for investigating CRHR1-mediated central nervous system functions and stress-related disorders.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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