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Antcin B

3CL Pro Inhibitor

Antcin B is a potent inhibitor of the SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro). It functions by binding to essential amino acid residues, including Leu141, Asn142, Glu166, and His163, through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby obstructing the protease's activity. This inhibition impedes the cleavage of viral polyproteins and restricts viral replication in host cells. Antcin B serves as a valuable tool for research related to COVID-19 and the development of antiviral strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	163597-25-9
Applications	3CL Pro Inhibitor
Formula	C₂₉H₄₀O₅
Molecular Weight	468.62
SMILES	C[C@@]12C3=C(C(C[C@@]1([H])[C@@H](C(CC2)=O)C)=O)[C@@]4([H])[C@](CC3=O)([C@@](CC4)([H])[C@H](C)CCC(C(C)C(O)=O)=C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.