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Anti-HGF/SF Antibody (TAK-701)
TAK-701 is a humanized monoclonal antibody that targets human hepatocyte growth factor (HGF), exhibiting potential antineoplastic properties. This antibody is specifically designed to bind to HGF, a multifunctional cytokine involved in cell growth, motility, and morphogenesis of various tissues, with a particular focus on its role in tumorogenesis. TAK-701 has shown efficacy in reversing gefitinib resistance in non-small-cell lung cancer (NSCLC), suggesting its utility in enhancing response rates to conventional therapies in resistant cancer cells. This makes it a valuable tool for research in cancer treatment modalities, particularly in understanding and overcoming drug resistance mechanisms in NSCLC.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Synonyms | TAK-701 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.