Fig. 1 · Structure
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Anti-infective agent 3
Anti-infective Agent
Anti-infective agent 3 (compound 3l) is an effective antiparasitic compound targeting Plasmodium falciparum and Trypanosoma brucei rhodesiense, exhibiting IC50 values of 0.47 μM and 0.13 μM, respectively. Additionally, it demonstrates significant antimycobacterial activity against Mycobacterium smegmatis, with a minimum inhibitory concentration (MIC) of 4 μg/mL. This compound serves as a valuable tool in the research of anti-infective therapies and the study of parasitic and mycobacterial infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2521629-86-5 |
| Applications | Anti-infective Agent |
| Formula | C14H7ClN2O2 |
| Molecular Weight | 270.67 |
| SMILES | O=C1C=C(C(C2=CC=CC=C12)=O)C3=CN=C(N=C3)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.