Anti-inflammatory agent 18

Catalog No.: A65158
Anti-inflammatory Agent
Anti-inflammatory agent 18, an established anti-inflammatory agent, demonstrates inhibitory activity with an IC50 of 15.94 μM against HMGB1-induced later inflammation. This compound is valuable in research applications focused on later inflammatory diseases, including coronavirus-related conditions such as COVID-19 and sepsis. Its mechanism of action supports investigations into potential therapeutic strategies for managing chronic inflammatory responses.
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Size Stock
5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAnti-inflammatory agent 18, an established anti-inflammatory agent, demonstrates inhibitory activity with an IC50 of 15.94 μM against HMGB1-induced later inflammation. This compound is valuable in research applications focused on later inflammatory diseases, including coronavirus-related conditions such as COVID-19 and sepsis. Its mechanism of action supports investigations into potential therapeutic strategies for managing chronic inflammatory responses.
Product Information
Catalog NumA65158
FormulaC30H50O6
Molecular Weight506.71
CAS Number2873386-66-2
SMILESC[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])CC(C)([C@@H]([C@H]4O)O)C)C)C)([H])[C@](C)([C@](CC1)([H])[C@](C)(O)CO)CCC(O)=O
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