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anti-TNBC agent-13

Catalog No.: A26933
Ferroptosis Inducer
Anti-TNBC agent-13 is a ferroptosis inducer designed to target and inhibit GPX4 activity. By promoting the accumulation of lipid peroxides, it triggers cell death specifically in triple-negative breast cancer (TNBC) cells. This compound serves as a valuable research tool for studying ferroptosis and its therapeutic potential in TNBC.
anti-TNBC agent-13 3060507-88-9 Ferroptosis Inducer
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAnti-TNBC agent-13 is a ferroptosis inducer designed to target and inhibit GPX4 activity. By promoting the accumulation of lipid peroxides, it triggers cell death specifically in triple-negative breast cancer (TNBC) cells. This compound serves as a valuable research tool for studying ferroptosis and its therapeutic potential in TNBC.
Product Information
Catalog NumA26933
FormulaC45H56N4O15S3
Molecular Weight989.14
CAS Number3060507-88-9
SMILESO=S(C1=[N+]([O-])ON=C1OCCN2CCN(C(CCSSCCC(O[C@H]3[C@H](/C=C/C=C/C=C/C(O4)=C(C)C(OC)=CC4=O)O[C@@]5(C)[C@@H](CC)O[C@@]3(C)[C@@H]5OC(C)=O)=O)=O)CC2)(C6=CC=CC=C6)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Metabolism > Ferroptosis