Fig. 1 · Structure

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Anticancer agent 183

MMP-9 Inhibitor

Anticancer agent 183 is a potent matrix metalloproteinase-9 (MMP-9) inhibitor that demonstrates over 75% inhibition of MMP-9 activity at a concentration of 100 μg/mL. It exhibits significant anticancer effects with an IC50 value of less than 0.14 μM against the A549 lung cancer cell line. Additionally, Anticancer agent 183 promotes apoptosis, making it a valuable reagent for research in cancer biology and therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3018960-58-9
Applications MMP-9 Inhibitor
Formula C19H18N4O4S
Molecular Weight 398.44
SMILES
O=C(NC1=CC=CC=C1)CSC2=NN=C(COC3=CC=CC=C3NC(C)=O)O2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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