Fig. 1 · Structure
Documents & Downloads
Anticancer agent 7
PP2A Modulator
Anticancer Agent 7 is a PP2A modulator that facilitates the translocation of the FOXO1 transcription factor to the nucleus. This compound exhibits significant anti-proliferative activity against H1650 lung cancer cells, demonstrating an IC50 value of 5 μM. It serves as a valuable tool in cancer research, particularly in studies focused on signaling pathways involving PP2A and FOXO1.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2088956-21-0 |
| Applications | PP2A Modulator |
| Formula | C24H19Cl2F3N2O5S |
| Molecular Weight | 575.38 |
| SMILES | O[C@@H]1[C@@](COC[C@H]1NS(=O)(C2=CC=C(C=C2)OC(F)(F)F)=O)([H])N3C4=CC=C(Cl)C=C4C5=CC(Cl)=CC=C53 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.