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Antileishmanial agent-23

Trypanothione Reductase Inhibitor

Antileishmanial agent-23 is a potent and selective inhibitor of trypanothione reductase (TR), exhibiting an IC50 value of 2.24 ± 0.52 μM. This compound effectively inhibits the growth of Leishmania spp., Trypanosoma cruzi, and Trypanosoma brucei. It serves as a valuable tool for research in parasitology and the development of anti-parasitic therapies targeting trypanothione metabolism.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	745033-86-7
Applications	Trypanothione Reductase Inhibitor
Formula	C₂₀H₁₇N₃O₄S₂
Molecular Weight	427.50
SMILES	COC1=CC=C(C=C1)C2=NCC(S2)CSC3=NN=C(C4=CC5=C(OCO5)C=C4)O3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.