Fig. 1 · Structure
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Antimalarial agent 13
Antimalarial Agent
Antimalarial agent 13 is a potent inhibitor of Plasmodium falciparum. It demonstrates significant antimalarial activity with an EC50 value of 124 nM, while also exhibiting activity against HepG2 cells with an EC50 of 2.5 μM. This compound is valuable for research applications aimed at understanding and developing treatments for malaria.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 431884-01-4 |
| Applications | Antimalarial Agent |
| Formula | C19H15ClN4O |
| Molecular Weight | 350.80 |
| SMILES | ClC1=CC=CC(NC2=NC(NCC3=CC=CO3)=C4C=CC=CC4=N2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.