Fig. 1 · Structure
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Antimalarial agent 19
Antimalarial Active Agent
Antimalarial agent 19 is a potent antimalarial active agent targeting Plasmodium species. It exhibits activity against the blood stage of P. falciparum K1 and P. berghei, with EC50 values of 0.3 µM and 15.3 µM, respectively. This compound demonstrates favorable properties, including good aqueous solubility, intestinal permeability, and microsomal stability, making it a valuable tool for antimalarial drug discovery and research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2897630-89-4 |
| Applications | Antimalarial Active Agent |
| Formula | C22H33Cl2N5S |
| Molecular Weight | 470.50 |
| SMILES | CC1=CC=C(C=C1)C2=CC3=C(C(NCCCN(C)C)=NC(NC(C)(C)C)=N3)S2.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.