Fig. 1 · Structure
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Antimalarial agent 26
Antimalarial Agent
Antimalarial Agent 26 is a 1,4-naphthoquinone derivative that exhibits significant antimalarial activity, specifically targeting Plasmodium falciparum. This compound demonstrates cytotoxic effects on malaria-infected cells while maintaining selectivity for non-malignant mammalian cell lines. Additionally, Antimalarial Agent 26 effectively inhibits P. berghei-induced parasitemia in vivo, making it a valuable tool for researching malaria treatments and interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2299199-56-5 |
| Applications | Antimalarial Agent |
| Formula | C20H22N4O3 |
| Molecular Weight | 366.41 |
| SMILES | O=C1C=C(C(C2=C1C=CC=C2)=O)NCCN3N=NC(C4(CCCCC4)O)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.