Fig. 1 · Structure
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Antimalarial agent 29
Antimalarial Agent
Antimalarial Agent 29 is a potent inhibitor of Plasmodium berghei liver stage parasites, demonstrating an effective EC50 value of 5.2 μM. This compound is utilized in research focused on uncovering novel therapeutic strategies against malaria, particularly during the critical liver stage of the parasite's life cycle. Its application holds promise for advancing the development of targeted antimalarial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2821078-81-1 |
| Applications | Antimalarial Agent |
| Formula | C18H10ClF3N2 |
| Molecular Weight | 346.73 |
| SMILES | FC(F)(C1=CC=CC(C2=NC=CC3=C2NC4=C3C=C(C=C4)Cl)=C1)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.