Fig. 1 · Structure

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Antimalarial agent 36

Antimalarial Agent

Antimalarial agent 36 is an effective antimalarial compound that demonstrates potent activity with EC50 values of 58 nM and 42 nM against Dd2 and 3D7 Plasmodium falciparum strains, respectively. It specifically targets the EphA2 receptor, contributing to its mechanism of action. This agent is suitable for research applications aimed at studying antimalarial drug development and mechanisms of resistance.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2982633-03-2
Applications Antimalarial Agent
Formula C31H29ClF3N5O2S
Molecular Weight 628.11
SMILES
O=C(C1=CC(C2=CC=CS2)=CN=C1)NC3=CC(Cl)=CC(C(NC4=CC=C(C(C(F)(F)F)=C4)CN5CCN(CC5)CC)=O)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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