Fig. 1 · Structure
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Antimalarial agent 8
Antimalarial Agent
Antimalarial agent 8 is a novel orally active compound targeting malaria parasites. This agent exhibits potent in vitro activity against Plasmodium falciparum, demonstrating efficacy at an oral dose of 40 mg/kg in in vivo mouse models of malaria. Its promising bioactivity supports further research and development in malaria therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2715222-97-0 |
| Applications | Antimalarial Agent |
| Formula | C22H21Cl3N4O |
| Molecular Weight | 463.79 |
| SMILES | O=C(C1=CC2=C(NC3=C2C=CC=C3C)C(C4=CC(Cl)=C(Cl)C=C4)=N1)NCCNC.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.