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Antitrypanosomal agent 27

Antitrypanosomal Agent

Antitrypanosomal Agent 27 is a quinazoline compound that targets the protozoan parasite Trypanosoma brucei, responsible for human African trypanosomiasis. This agent demonstrates potent antitrypanosomal activity with a GI50 value of 31 nM, making it a valuable tool for research into trypanosomiasis treatment and mechanisms of parasite resistance. Its efficacy positions Antitrypanosomal Agent 27 as a significant compound for studying and developing potential therapies against this neglected tropical disease.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2148927-96-0
Applications	Antitrypanosomal Agent
Formula	C₂₆H₂₃F₃N₆O₂
Molecular Weight	508.50
SMILES	CN1CCN(CC1)C2=CC=CC(C3=CC=C4N=CN=C(C4=C3)NC5=CC=C(C(C(F)(F)F)=C5)[N+]([O-])=O)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.