Fig. 1 · Structure

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Antitrypanosomal agent 28

Antitrypanosomal Agent

Antitrypanosomal agent 28 is a potent trypanocidal agent targeting Trypanosoma cruzi. Its mechanism involves the induction of reactive oxygen species (ROS) and subsequent mitochondrial damage, with an IC₅₀ of 49.4 μM. In addition to its antitrypanosomal properties, this compound demonstrates broad-spectrum anti-tumor activity, particularly effective against leukemia, colon cancer, and breast cancer cell lines. Antitrypanosomal agent 28 is suitable for research focused on both anti-cancer and anti-trypanosomal activities.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2413738-47-1
Applications Antitrypanosomal Agent
Formula C27H21NO
Molecular Weight 375.46
SMILES
CC1=NC2=CC=CC=C2C(/C=C/C3=CC=CC=C3)=C1C(/C=C/C4=CC=CC=C4)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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