Fig. 1 · Structure

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Antitrypanosomal agent 4

Antitrypanosomal Agent

Antitrypanosomal agent 4 is a potent agent targeting Trypanosoma cruzi and Trypanosoma brucei brucei, exhibiting IC50 values of 1.2 μM and 70 nM, respectively. This compound effectively crosses the blood-brain barrier, making it a valuable candidate for research into trypanosomiasis treatments. Additionally, Antitrypanosomal agent 4 features an alkyne group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc), expanding its utility in click chemistry applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2456427-48-6
Applications Antitrypanosomal Agent
Formula C18H14ClN3O5S
Molecular Weight 419.84
SMILES
OCCC#CC1=CC(Cl)=CN2C1=NC(CS(=O)(C3=CC=CC=C3)=O)=C2[N+]([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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