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Antitrypanosomal agent 6

Antitrypanosomal Agent

Antitrypanosomal agent 6 is a potent compound targeting Trypanosoma brucei, exhibiting an IC50 value of 0.47 μM, which is over two-fold more effective than Nifurtimox. This agent demonstrates favorable ADME properties and strong interaction with DNA through selective binding to AT-rich regions. It serves as a valuable tool for research in trypanosomiasis and related parasitic diseases.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2492436-35-6
Applications	Antitrypanosomal Agent
Formula	C₂₂H₂₉Cl₂N₅O
Molecular Weight	450.40
SMILES	CCN(CCOC1=CC=C(C2=NC3=CC(C4=NCCN4)=CC=C3N2)C=C1)CC.[H]Cl.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.