Antitumor agent-100 hydrochloride is a potent apoptosis inducer targeting PDE3A-SLFN12, exhibiting an IC50 of 0.3 μM. This compound binds to the enzyme pocket of PDE3A, facilitating the recruitment and stabilization of SLFN12, which inhibits protein translation and initiates apoptotic pathways. It serves as a valuable tool in oncology research, particularly in studies focused on apoptosis and antitumor mechanisms.
Antitumor agent-100 hydrochloride is a potent apoptosis inducer targeting PDE3A-SLFN12, exhibiting an IC50 of 0.3 μM. This compound binds to the enzyme pocket of PDE3A, facilitating the recruitment and stabilization of SLFN12, which inhibits protein translation and initiates apoptotic pathways. It serves as a valuable tool in oncology research, particularly in studies focused on apoptosis and antitumor mechanisms.
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