Antitumor agent-100 (compound A6) is an orally bioavailable apoptosis inducer targeting PDE3A and SLFN12, with an IC50 value of 0.3 μM. This compound functions by binding to the PDE3A enzyme pocket, effectively recruiting and stabilizing SLFN12, which disrupts protein translation and promotes apoptosis. Antitumor agent-100 demonstrates significant potential in cancer research applications, particularly in programs focusing on apoptosis regulation and tumor suppression mechanisms.
Antitumor agent-100 (compound A6) is an orally bioavailable apoptosis inducer targeting PDE3A and SLFN12, with an IC50 value of 0.3 μM. This compound functions by binding to the PDE3A enzyme pocket, effectively recruiting and stabilizing SLFN12, which disrupts protein translation and promotes apoptosis. Antitumor agent-100 demonstrates significant potential in cancer research applications, particularly in programs focusing on apoptosis regulation and tumor suppression mechanisms.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
