Fig. 1 · Structure
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Antitumor agent-127
Cat. No.
A77575
CAS
3034861-58-7
ROR1 Ligand
Antitumor agent-127 is a macrocyclic peptide that targets the ROR1 receptor. It exhibits nanomolar affinity for ROR1, demonstrating effective binding and substantial internalization in 786-O and MDA-MB-231 tumor cell lines. This compound is valuable for research in cancer biology, particularly in studies focused on ROR1-mediated signaling pathways and potential therapeutic applications in tumors expressing ROR1.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 3034861-58-7 |
| Applications | ROR1 Ligand |
| Formula | C86H107N15O18S |
| Molecular Weight | 1670.92 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.