AP-C6 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), demonstrating a pIC50 of 6.5. This compound effectively inhibits human cGKII activity in a concentration-dependent manner in vitro. Additionally, AP-C6 enhances cAMP signaling through phosphodiesterase (PDE) inhibition, making it a valuable tool for research involving cGKII and related signaling pathways.
AP-C6 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), demonstrating a pIC50 of 6.5. This compound effectively inhibits human cGKII activity in a concentration-dependent manner in vitro. Additionally, AP-C6 enhances cAMP signaling through phosphodiesterase (PDE) inhibition, making it a valuable tool for research involving cGKII and related signaling pathways.
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