AP-C7

Catalog No.: A84801
cGKII Inhibtor
AP-C7 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.0. This compound demonstrates weak inhibition of cGKII-dependent anion secretion, making it a valuable tool for exploring the role of cGKII in cellular signaling pathways and its impact on various physiological processes. AP-C7 can be utilized in research focused on cardiovascular biology, gastrointestinal function, and related areas studying cGMP signaling mechanisms.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAP-C7 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.0. This compound demonstrates weak inhibition of cGKII-dependent anion secretion, making it a valuable tool for exploring the role of cGKII in cellular signaling pathways and its impact on various physiological processes. AP-C7 can be utilized in research focused on cardiovascular biology, gastrointestinal function, and related areas studying cGMP signaling mechanisms.
Product Information
Catalog NumA84801
FormulaC18H15N5O
Molecular Weight317.34
CAS Number2234275-84-2
SMILESN1(C2=CC=C(C3=NC(NCC4=CC=CO4)=NC=C3)C=C2)C=CN=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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