Fig. 1 · Structure
Documents & Downloads
Apelin-36(rat, mouse)
APJ Agonist
Apelin-36 (rat, mouse) is a potent agonist of the APJ receptor, an orphan G protein-coupled receptor. It exhibits high affinity for APJ receptors with an IC50 of 5.4 nM and effectively inhibits cAMP production, with an EC50 of 0.52 nM. Research applications include studies on metabolic regulation and cardiovascular function, as well as exploration of its role in blocking the entry of certain HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing the APJ receptor.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 230299-95-3 |
| Applications | APJ Agonist |
| Formula | C185H304N68O43S |
| Molecular Weight | 4200.89 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.