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Apicularen B

V-ATPase Inhibitor

Apicularen B is a potent V-ATPase inhibitor derived from the myxobacterium Archangium gephyra. This cytotoxic macrolide exhibits significant biological activity relevant to the study of V-ATPase-related disorders, including osteopetrosis. Researchers can utilize Apicularen B to investigate the mechanisms underlying these diseases and explore potential therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	220757-06-2
Applications	V-ATPase Inhibitor
Formula	C₃₃H₄₄N₂O₁₁
Molecular Weight	644.71
SMILES	O=C(O[C@H]1C/C=C/NC(/C=C\C=C/CC)=O)C(C(C[C@@](O[C@@]2([H])C1)([H])C[C@H](C2)O[C@H](O[C@@H]3CO)[C@@H]([C@H]([C@@H]3O)O)NC(C)=O)=CC=C4)=C4O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.