Fig. 1 · Structure
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APJ receptor agonist 8
APJ receptor Agonist
APJ Receptor Agonist 8 is a potent agonist of the APJ receptor, known for its ability to enhance load-independent cardiac contractility in isolated perfused rat hearts. This compound is valuable for research focused on cardiac physiology and the exploration of therapeutic strategies for heart failure and other cardiovascular disorders. Its specific mechanism of action makes it a useful tool for studies investigating the role of APJ signaling in cardiac function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2049973-39-7 |
| Applications | APJ receptor Agonist |
| Formula | C24H27N7O5S |
| Molecular Weight | 525.58 |
| SMILES | O[C@H](C1=NC=C(C)C=N1)[C@H](C)S(NC2=NN=C(C3=CC=CC(C)=N3)N2C4=C(C=CC=C4OC)OC)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.