Fig. 1 · Structure
Documents & Downloads
APOL1-IN-1
APOL1 Inhibitor
APOL1-IN-1 is an apolipoprotein L1 (APOL1) inhibitor, targeting the modulation of APOL1 activity. This compound has demonstrated potential in scientific investigations focused on focal segmental glomerulosclerosis (FSGS) and non-diabetic kidney disease (NDKD). By inhibiting APOL1, it may help elucidate the mechanisms underlying these kidney disorders, providing valuable insights for therapeutic development.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2446817-72-5 |
| Applications | APOL1 Inhibitor |
| Formula | C21H20FN3O3 |
| Molecular Weight | 381.40 |
| SMILES | O=C(N[C@@H]1C(NC[C@H]1O)=O)CCC2=C(C3=CC=C(F)C=C3)NC4=C2C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.