Apoptosis Inducer 46 targets apoptotic pathways to induce cell death selectively in metastatic triple-negative breast cancer (TNBC) cells. It demonstrates potent growth inhibitory effects, specifically causing G2/M phase cell cycle arrest and promoting apoptotic cell death in MDA-MB-231 cells. Additionally, Apoptosis Inducer 46 inhibits NF-κB nuclear translocation, highlighting its potential for research applications in the study of TNBC.
Apoptosis Inducer 46 targets apoptotic pathways to induce cell death selectively in metastatic triple-negative breast cancer (TNBC) cells. It demonstrates potent growth inhibitory effects, specifically causing G2/M phase cell cycle arrest and promoting apoptotic cell death in MDA-MB-231 cells. Additionally, Apoptosis Inducer 46 inhibits NF-κB nuclear translocation, highlighting its potential for research applications in the study of TNBC.
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