Fig. 1 · Structure
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AQ-RA 741
M 2 Antagonist
AQ-RA 741 is a potent and selective M2 antagonist that effectively inhibits vagally or agonist-induced bradycardia in various animal models, including rats, cats, and guinea pigs. This compound is valuable in the study of bradycardic disorders, providing insights into potential therapeutic strategies for managing heart rate irregularities. Its specificity towards the M2 muscarinic receptor makes it a critical tool for investigating cholinergic signaling pathways in cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 123548-16-3 |
| Applications | M 2 Antagonist |
| Formula | C27H37N5O2 |
| Molecular Weight | 463.61 |
| SMILES | CCN(CC)CCCCC(CC1)CCN1CC(N2C3=CC=CC=C3C(NC4=CC=CN=C24)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.