AR-A014418-d3 is a deuterium-labeled analogue of the selective GSK3β inhibitor AR-A014418. It exhibits potent ATP-competitive inhibition with an IC50 of 104 nM and a Ki of 38 nM. This stable isotope form is useful for tracking and quantifying GSK3β activity in biological systems, and it serves as a valuable tool in research focused on cellular signaling, metabolism, and neurodegenerative diseases.
AR-A014418-d3 is a deuterium-labeled analogue of the selective GSK3β inhibitor AR-A014418. It exhibits potent ATP-competitive inhibition with an IC50 of 104 nM and a Ki of 38 nM. This stable isotope form is useful for tracking and quantifying GSK3β activity in biological systems, and it serves as a valuable tool in research focused on cellular signaling, metabolism, and neurodegenerative diseases.
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