Fig. 1 · Structure

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AR-HO47108

Na+/K+ ATPase Inhibitor

AR-HO47108 is a reversible inhibitor of the Na+/K+ ATPase, primarily targeting the potassium ion binding site within gastric wall cells. By competitively blocking this site, AR-HO47108 effectively reduces gastric acid secretion, making it a valuable tool for investigating conditions associated with excessive gastric acid, such as peptic ulcers. This compound is particularly useful for research into gastric physiology and related gastrointestinal disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 248281-68-7
Applications Na+/K+ ATPase Inhibitor
Formula C20H24N4O
Molecular Weight 336.43
SMILES
O=C(C1=CN2C(C(NCC3=C(C)C=CC=C3CC)=C1)=NC(C)=C2C)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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