Fig. 1 · Structure
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Arachidonoyl Serinol
MAGL Inhibitor
Arachidonoyl Serinol is a selective inhibitor of monoacylglycerol lipase (MAGL), an enzyme critical in the metabolism of endocannabinoids. It effectively inhibits the hydrolysis of [3H]2-oleoylglycerol and [3H]anandamide, with IC50 values approximately at 70 μM. This compound is widely utilized in research focused on the endocannabinoid system and its implications in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 183718-70-9 |
| Applications | MAGL Inhibitor |
| Formula | C23H39NO3 |
| Molecular Weight | 377.56 |
| SMILES | O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NC(CO)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.