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Archangelicin

NFAT Inhibitor

Archangelicin is a potent inhibitor of the nuclear factor of activated T cells (NFAT) with an IC50 of 9 μM. This compound also functions as an inhibitor of cAMP-phosphodiesterase (cAMP-PDE) with an IC50 greater than 400 μM. Archangelicin demonstrates significant antitumor and anti-inflammatory properties, making it valuable for research in immunology and cancer biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2607-56-9
Applications	NFAT Inhibitor
Formula	C₂₄H₂₆O₇
Molecular Weight	426.46
SMILES	C/C=C(C)\C(O[C@H]1[C@@H](C(OC(/C(C)=C\C)=O)(C)C)OC(C=C2)=C1C(O3)=C2C=CC3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.