Fig. 1 · Structure
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Arecaidine propargyl ester hydrobromide
Apoptosi
Arecaidine propargyl ester hydrobromide is an agonist of M2 muscarinic acetylcholine receptors, exhibiting significant inhibitory effects on tumor cell proliferation. This compound has demonstrated the ability to induce apoptosis and stimulate the production of reactive oxygen species (ROS) in ovarian cancer cells in vitro. Additionally, it can cause cell cycle arrest at the G2/M phase and increase the occurrence of abnormal mitosis, particularly in ovarian surface epithelial cells with elevated M2 receptor levels. Arecaidine propargyl ester hydrobromide also shows potential cardiovascular effects by lowering arterial blood pressure, suggesting its relevance for pharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 116511-28-5 |
| Applications | Apoptosi |
| Formula | C10H14BrNO2 |
| Molecular Weight | 260.13 |
| SMILES | O=C(C1=CCCN(C1)C)OCC#C.Br |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.