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Arhododendric acid A

PTP1B Inhibitor

Arhododendric acid A is a triterpenoid that acts as a selective inhibitor of the protein tyrosine phosphatase PTP1B, exhibiting an IC50 of 6.3 μM. This compound plays a significant role in the modulation of insulin signaling pathways and is primarily utilized in research relevant to type 2 diabetes. Its inhibition of PTP1B supports investigations into glucose metabolism and insulin resistance, making it a valuable reagent for diabetes-related studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1402543-98-9
Applications	PTP1B Inhibitor
Formula	C₃₀H₄₆O₄
Molecular Weight	470.68
SMILES	C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CCC([C@@H]4C)=C)C(O)=O)=CC[C@]1([H])[C@@]5([C@@]([C@@](C)([C@H](CC5)O)CO)([H])CC2)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.