Fig. 1 · Structure
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ARN-6039
Cat. No.
A77586
CAS
1675206-11-7
RORγ inverse agonist
ARN-6039 is an orally active inverse agonist of RORγ, a transcription factor involved in the regulation of various immune responses. This compound demonstrates potential in modulating immune activity and may be effective in the treatment of autoimmune demyelinating diseases. It serves as a valuable tool for research aimed at understanding the role of RORγ in immune-related disorders and developing therapeutic strategies targeting these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inverse Agonist |
| CAS Number | 1675206-11-7 |
| Applications | RORγ inverse agonist |
| Formula | C21H21F3N2O3 |
| Molecular Weight | 406.40 |
| SMILES | COC1=C(C=C(C2=C1)CC(C2=O)CC3=NC=CC=C3C(F)(F)F)N4CCOCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.