Fig. 1 · Structure
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ARS-1620 intermediate
Intermediate
ARS-1620 intermediate is a critical precursor in the synthesis of the K-RasG12C inhibitor ARS1620. This intermediate facilitates the production of compounds targeting the oncogenic K-RasG12C mutation, relevant in various cancers. It serves as a valuable tool for chemical researchers focusing on cancer therapeutics and targeted drug development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1698027-20-1 |
| Applications | Intermediate |
| Formula | C17H19BrClFN4O2 |
| Molecular Weight | 445.71 |
| SMILES | ClC1=C(Br)C(F)=C(N=CN=C2N3CCN(C(OC(C)(C)C)=O)CC3)C2=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.