Biological Activity
AS-2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with IC50 value of 21 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.1 mL | 115.51 mL | 231.02 mL |
0.5 mM | 4.62 mL | 23.1 mL | 46.2 mL |
1 mM | 2.31 mL | 11.55 mL | 23.1 mL |
5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
*The above data is based on the productmolecular weight 432.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17186 |
---|---|
Actions | Inhibitor |
M. Wt | 432.86 |
Formula | C19H20N6O4.HCl |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1287665-60-4 |
Synonyms | AS2444697, AS-2444697 |
SMILES | O=C(N)C2=NN(C=C2NC(C3=COC(C4=CC=NC(C)=C4)=N3)=O)C1CCOCC1.Cl |
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