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Other Forms

Form	MW
AS2690168 (freebase) This page	346.31
AS2690168 hydrochloride	382.77

AS2690168 (freebase)

RANKL Inhibitor

AS2690168 (freebase) is a potent RANKL signal transduction inhibitor that effectively suppresses RANKL-induced osteoclastogenesis in RAW264 cells. This compound serves as a valuable tool in investigating mechanisms of pathological osteolysis and can aid in the study of bone resorption disorders. Its oral bioactivity makes it suitable for in vivo research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1393999-78-4
Applications	RANKL Inhibitor
Formula	C₁₇H₁₃F₃N₄O
Molecular Weight	346.31
SMILES	FC1=CC(F)=C(CNC2=C(OC)C=NC(C3=NC=CC=C3)=N2)C(F)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.