Target & Activity
| Target | Activity | Value |
|---|---|---|
| sPLA2 | Ki | 2.5 nM |
| 5-HT2A Receptor | Ki | 0.06 nM |
| 5-HT2C Receptor | Ki | 0.03 nM |
| 5-HT7 Receptor | Ki | 0.13 nM |
| D2 Receptor | Ki | 1.3 nM |
| D3 Receptor | Ki | 0.42 nM |
| D4 Receptor | Ki | 1.1 nM |
7 targets · Scroll to view more
Fig. 1 · Structure
Documents & Downloads
Asenapine HCl
Cat. No.
A15002
CAS
1412458-61-7
adrenergic receptor/5-HT receptor inhibitor
Asenapine hydrochloride inhibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1412458-61-7 |
| Applications | adrenergic receptor/5-HT receptor inhibitor |
| Formula | C17H17Cl2NO |
| Molecular Weight | 322.23 |
| Synonyms | Saphris hydrochloride |
| SMILES | CN1CC2C(C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.