Fig. 1 · Structure
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ASN-1377642
NK1 Receptor Antagonist
ASN-1377642 is an NK1 receptor antagonist with a Ki value of 251 nM. This compound demonstrates antitumor activity, particularly in breast cancer cells that exhibit high expression of the NK1 receptor. ASN-1377642 may facilitate research into targeted cancer therapies and the role of neurokinin signaling in tumor progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 337505-63-2 |
| Applications | NK1 Receptor Antagonist |
| Formula | C21H16ClN5OS |
| Molecular Weight | 421.90 |
| SMILES | O=C(NC1=CC=CC(Cl)=C1)CSC2=NN=C(C3=CC=NC=C3)N2C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.