AST 487

Catalog No.: A15003

RET kinase inhibitor

AST 487 Chemical Structure

CAS NO. 630124-46-8

AST487 is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret.

Availability: In stock

Package Price Qty
5 mg
$220.00
10 mg
$400.00
50 mg
$820.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AST487 is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.88 mL 94.42 mL 188.84 mL
0.5 mM 3.78 mL 18.88 mL 37.77 mL
1 mM 1.89 mL 9.44 mL 18.88 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 529.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15003
Actions Inhibitor
M. Wt 529.56
Formula C26H30F3N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 630124-46-8
Synonyms NVP-AST 487
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F

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