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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15003 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 529.56 |
| Formula | C26H30F3N7O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 630124-46-8 |
| Synonyms | NVP-AST 487 |
| SMILES code | CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)NC3=CC=C(C=C3)OC4=NC=NC(=C4)NC)C(F)(F)F |
| Chemical Name | 1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea |
Description |
AST487 is a Ret kinase inhibitor/FLT3 inhibitor with IC50 of 0.88 uM for Ret. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.88 mL | 94.42 mL | 188.84mL |
| 0.5 mM | 3.78 mL | 18.88 mL | 37.77 mL |
| 1 mM | 1.89 mL | 9.44 mL | 18.88 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
*The above data is based on the productmolecular weight 529.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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