Fig. 1 · Structure
Documents & Downloads
Ataciguat
sGC Activator
Ataciguat is a soluble guanylate cyclase (sGC) activator that functions independently of nitric oxide. It specifically activates the ferric heme-iron redox form of sGC, leading to increased production of cyclic GMP (cGMP). This compound demonstrates significant vasodilatory effects and is useful in research applications related to cardiovascular function and regulation of vascular tone.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 254877-67-3 |
| Applications | sGC Activator |
| Formula | C21H19Cl2N3O6S3 |
| Molecular Weight | 576.49 |
| Synonyms | HMR-1766 |
| SMILES | O=C(NC1=CC=C(S(=O)(N2CCOCC2)=O)C=C1)C3=CC(Cl)=CC=C3NS(=O)(C4=CC=C(Cl)S4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.