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ATX-IN-2

ATX Inhibitor

ATX-IN-2 is a potent and orally active inhibitor of autotaxin (ATX) with an IC50 value of 3.27 nM. It effectively reduces the secretion of lysophosphatidic acid (LPA), making it a valuable tool for studying ATX-mediated diseases. Its applications include research into inflammation and pulmonary fibrosis, providing insights into potential therapeutic strategies targeting these conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3076224-81-9
Applications	ATX Inhibitor
Formula	C₃₀H₂₉D₃FN₉O₂S₂
Molecular Weight	636.78
SMILES	O=C(N1CC2(COC2)C1)C3(CC3)N4CCN(C(S5)=NN6C5=NC(CC)=C6N(C([2H])([2H])[2H])C7=NC(C8=CC=C(F)C=C8)=C(C#N)S7)CC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.