Fig. 1 · Structure
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ATX inhibitor 10
ATX Inhibitor
ATX Inhibitor 10 is a potent inhibitor of autotaxin (ATX), a critical enzyme involved in the regulation of lysophosphatidic acid (LPA) signaling. This compound is a nitrogen-containing heterocyclic molecule that may provide new avenues for research into ATX-related pathologies, including fibrosis, arthritis, neurodegeneration, neuropathic pain, and cancer. Its selective inhibition of ATX activity makes it a valuable tool for studying the therapeutic potential in various disorders associated with dysregulated LPA signaling.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2648969-30-4 |
| Applications | ATX Inhibitor |
| Formula | C23H20F3N9O2 |
| Molecular Weight | 511.46 |
| SMILES | FC(C1=CC2=C(C[C@@H](NC3=NC=C(C4=NN=C(CC(N5CCC(N=NN6)=C6C5)=O)O4)C=N3)C2)C=C1)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.