Fig. 1 · Structure
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ATX inhibitor 13
ATX Inhibitor
ATX Inhibitor 13 is a potent inhibitor targeting autotaxin (ATX) with an IC50 value of 3.4 nM. This compound effectively inhibits cell proliferation and migration, and induces apoptosis along with G2 phase cell cycle arrest in RAW264.7 cells. Additionally, ATX Inhibitor 13 suppresses tumor cell colony formation, making it a valuable tool for research in cancer biology and inflammation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2485779-34-6 |
| Applications | ATX Inhibitor |
| Formula | C31H35Cl2N5O3 |
| Molecular Weight | 596.55 |
| SMILES | O=C(OCC1=CC(Cl)=CC(Cl)=C1)NC2=C(CC)N=C3C(C)=CC(C4=CC=C(CN5CCN(CCO)CC5)C=C4)=CN32 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.