Fig. 1 · Structure
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ATX inhibitor 14
Autotaxin Inhibitor
ATX Inhibitor 14 is a potent autotaxin (ATX) inhibitor, displaying an IC50 value of 0.41 nM. This indole-based carbamate derivative demonstrates significant inhibitory activity, making it a valuable tool for research into conditions related to fibrosis. Its selective modulation of ATX activity may aid in elucidating the role of this enzyme in fibrosis-related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2484811-39-2 |
| Applications | Autotaxin Inhibitor |
| Formula | C26H26Cl2N4O3S |
| Molecular Weight | 545.48 |
| SMILES | O=C(NC1=CN(CC)C2=C1C=C(C3=NC(CN4CCOCC4)=CS3)C=C2)OCC5=CC(Cl)=CC(Cl)=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.