Fig. 1 · Structure
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ATX inhibitor 19
ATX inhibitor
ATX inhibitor 19 is a selective inhibitor of autotaxin (ATX) with an IC50 value of 156 nM. This compound effectively modulates lysophosphatidic acid (LPA) signaling, demonstrating significant biological activity in various cellular contexts. It is primarily utilized in research applications focused on cancer progression, inflammation, and other conditions associated with aberrant LPA pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2691937-01-4 |
| Applications | ATX inhibitor |
| Formula | C28H33ClN6O2S |
| Molecular Weight | 553.12 |
| SMILES | O=C(NC1=CN(CC)C2=C1C=C(C3=NC(CN4CCN(CCO)CC4)=CS3)C=C2)NCC5=CC=C(Cl)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.